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Tablets of Etizolam buy online from chinese vendor!
Etizolam or as it is also called Etilaam, Etizola, Sedekopan, Etizest, Pasaden or Depas is thienodiazepine drug. It includes anticonvulsant, hypnotic and anxiolytic properties. Etizolam could be compared by its properties with alprazolam. It is legal in India, Italy and Japan. There are several etizolam forms: etizolam tablets, powder and liquid. It is aimed to treat such diseases as insomnia, panic disorder and other kinds of disorders. Using etizolam is a great decision when treating panic attacks and anxiety. Etizolam is not included into the list of controlled research chemicals in most countries around the world. That is why it is highly popular among research chemicals vendors.
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What is etizolam
Etizolam is included into the category of short-acting psychoactive research chemicals. Etizolam pellets are in an thienodiazepine class and is an analog of benzodiazepine. The difference in their molecules is in rings – etizolam has replaced benzene ring by a thiophene ring and triazole ring has been fused, making the drug a thienotriazolodiazepine. 1mg of etizolam is equal to 10mg of vallium. It binds to the GABAa receptors and potentiates GABA transmission and causes sedation of the central nervous system. This is what leads to its range of therapeutic and unwanted side effects.
Talking about the history of etizolame popularity, it could be seen on the graphics that this designer drug was the most popular in Japan, India, Sweden, the UK, the USA.
And the dynamics of etizolam popularity continues to grow, especially it could be noticed analyzing dynamics since 2012.
Biochemical Activity & Pharmacodynamics
Etizolam is 4-(2-chlorophenyl)-2-ethyl-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine, 1-methyl-6-o-chlorophenyl-8-ethyl-4H-s-triazolo[3,4-c]thieno[2,3-e]-1,4-diazepine or as it also called Y-7131 or Depas. Etizolame chemistry is quite similar to other short-acting benzodiazepines. In etizolame benzene ring is replaced to thiophene ring fused to a diazepine ring, which is a seven member ring with the two nitrogen constituents located at R1 and R4. a R2' fluorine substituted phenyl ring is bound to this structure at R5. There is also a methylated triazole ring fused to and incorporating R1 and R2 of its diazepine ring.
The absorption is fast and it takes from 30 min to 2 hours for its concentration in the blood-plasma. Etizolame like other thienodiazepines can have a great number of effects as it rises the
Pharmacology efficiency and effects of the neurotransmitter gamma aminobutyric acid (GABA) because it acts on its receptors. Prolactogenic effects provide increasing of prolactin in blood level. The existence of alpha-hydroxyetizolam, which is an active metabolite, provides longer duration (about 8 hours). Etizolam is purportedly metabolized by the hydroxylation of the methyl group and that of the ethyl group. There is no enough clarification of cytochrome P450 (CYP) enzymes which catalyze etizolam metabolism.
Etizolam half life is about 3.5 hours. Etizolam is rapidly methabolized andoxidized. It was noticed during etizolam experiences that it has similar characteristics to tricyclic antidepressants.
Etizolam hasn’t been researched enough and all of the effects described in the list are mainly based on the experience of etizolam consumers. If the dosage of etizolame is heavier, there will be much more effects. [
Among the most popular etizolam side effects there are:
We strongly recommend to be familiar with dosage and etizolam recreational dose before using etizolam
Light dose: 0.5-1mg
General dose: 1-2mg
Hard dose: 2-5 and more mg
For anxiety it 0.5 - 1.0mg up to 3 times a day.
For insomnia it is enough to have a dose of is 1-2mgs 30 minutes before retiring.
Onset: 10-40 min
Duration: 5-8 hours
After-effects: 6-24 hours
Etizolam is unscheduled in the USA and it is among legal research chemicals USA.You can buy etizolam online in USA. Etizolam is considered as a controlled designer drug in some of US states: Alabama, Arkansas,Florida, Mississippi, Virginia, Georgia and in Germany.
Talking about legal status of etizolam UK government controls this designer drug and it remains in the list of bath salts which are illegal for importation and selling. It is illegal in Japan and controlled in Poland and Switzerland.
Etizolam experience and product reviews
Analyzing stated information about etizolam from its current consumers, it is possible to have etizolam withdrawal that such research chemical can be compared with benzodiazepine drugs. It usually causes mild euphoria, anxiety and sedation. Some users mentioned memory loses while having strong doses of etizolam. Etizolam can be purchased both as pressed pills and in powder form.